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      <b>What are the early symptoms of gallstones?</b> If a gallstone lodges in a duct and causes a blockage, the resulting signs and symptoms may include: Sudden and rapidly intensifying pain in the upper right portion of your abdomen. Sudden and rapidly intensifying pain in the center of your abdomen, just below your breastbone. Back pain between your shoulder blades.
      <b>Does ursodiol need to be refrigerated?</b> The suspension is stable for 60 days at room temperature or refrigerated. To prepare a 60 mg/ml suspension: Open twelve 300-mg ursodiol capsules and wet with sufficient glycerin, USP. The suspension is stable for 35 days in the refrigerator (at 4 degrees C).
      <b>Does ursodiol dissolve gallstones?</b> During treatment with ursodiol for dissolution of gallstones, symptoms of biliary distress began to improve after three to six weeks. Gallstones will recur in about 50% of patients, but no consensus exists on management of patients after dissolution of their stones.
      <b>Can you take ursodiol without food?</b> It is best to take ursodiol with meals, unless otherwise directed by your doctor. Take this medicine for the full time of treatment, even if you begin to feel better. If you stop taking this medicine too soon, the gallstones may not dissolve as fast or may not dissolve at all.
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